The architecture of parallel fiber axons contacting cerebellar Purkinje neurons retains spatial information over long distances.Parallel fiber synapses can trigger local dendritic calcium spikes, but whether and how this calcium signal leads to plastic changes that decode the parallel fiber input organization is unknown.By combining voltage and cal

Abstract Background Pakistan is one of only three countries where poliovirus circulation remains Porcelain Tag endemic.For the Pakistan Polio Eradication Program, identifying high risk districts is essential to target interventions and allocate limited resources.Methods Using a hierarchical Bayesian framework we developed a spatial Poisson hurdle m

Despite the importance of ex situ conservation programmes as highlighted in the Amphibian Scanner Conservation Action Plan, there are few empirical studies that examine the influence of captive conditions on the fitness of amphibians, even for basic components of enclosure design such as cover provision.Maintaining the fitness of captive amphibian

This paper presents the result of replacing natural course aggregate with recycled cement-sand brick (CSB) towards the mechanical properties of concrete.Natural aggregates were used in this study as a control sample to compare with recycled coarse aggregates.This study was also carried to determine the optimum proportion of coarse aggregates replac